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Introduction
Clinical presentation
Clin. aproach to ivestig. and menag. of UTI
Cortical scintigraphy in urinary tract infection
Cystigraphy in urinary tract infection
Vesicourethral reflux (VUR)
The grading systems for vesicourethral eflux
Detection of vesicourethral reflux
Micturating cystourethrography (MCUG)
Radionucleotide cystography (RNC)
Direct radionuclide cystography (DRC)
Indirect radionuclide cystography (IRC)
Dynamic renal scintigraphy in UTI
Practical problems in pediatric nucl.med.
Preparation
Dose schedule
Injection
Imobilisation/ sedation
Conclusion

6.2. DOSE SCHEDULE

The dose of isotope must be scaled down according to either body surface area or body weight. The use of age as a scaling factor is not recommended since the children in chronic renal failure may fail to grow normally [5].The radiopharmaceutical dose schedule suggested comes from the paediatric task group of European Association of Nuclear Medicine (EANM) (see Table 4a and 4 b) [5].

 

Table 4a. Radiopharmaceutical dose schedule in paediatric nephrourology

RADIOPHARMACEUTICAL

ADULTS (MBq)

MINIMUM PAEDIATRIC DOSE

99Mtc-DTPA(kidney)

200

20

99mTc-MAG3

100

15

99mTc-DMSA

80

15

99mTc-Pertechnetate (DIC)

20

20

Table 4.b Dosage recommendation of the Peridatric Task Group of the EANM as a fraction of adult administered activity:

3 kg =0.10
4 kg =0.14
6 kg =0.19
8 kg =0.23
10 kg =0.27
12 kg =0.32
14 kg =0.36
16 kg =0.40
18 kg =0.44
20 kg =0.46

22 kg =0.50
24 kg =0.53
26 kg =0.56
28 kg =0.58
30 kg =0.62
32 kg =0.65
34 kg =0.68
36 kg =0.71
38 kg =0.73
40 kg =0.76

 

42 kg = 0.78
44 kg = 0.80
46 kg = 0.82
48 kg = 0.85
50 kg = 0.88
52-54 kg =0.90
56-58 kg =0.92
60-62 kg =0.96
64-66 kg =0.98
68 kg = 0.99
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