4.2.2. RADIONUCLIDE CYSTOGRAPHY (RNC)

Although radionuclide cystography was clinically introduced in 1971, it was not until the advent of modern gamma cameras that a modification of the technique incorporating dynamic image became widely accepted [2,7]. Indications for radonuclide cystography are listed in Table 1.
RNC allows a greater than 90% success rate in predicting which patients will have spontaneous resolution of their VUR. The prediction is based on an increase in bladder volume at which VUR occurs on sequential examination. RNC has been recommended as the initial study in the examination of female child with UTI, for the screening of siblings of patients with VUR and in the evaluation of the child with myelomeningocele and is the preferred test for follow up studies [7].

Two forms of radionuclide cystography have been described: direct and indirect. Each method has advantages and disadvantages.