ROLE OF PORTAL HYPERTENSION IN MORTALITY OF THE PATIENTS WITH
M. Gribajčević, N. Vanis, N. Borovac, S. Gornjaković, N. Zubčević
and A. Pilav .
of Gastroenterohepatology, Clinical Center University of Sarajevo,
Bosnia and Herzegovina
of the esophageal varices (REV) is a very dangerous complication
of the portal hypertension, which seriously jeopardize life of
the patients. Aim of this study is to point out the mortality
rate of the patients with cirrhosis due to variceal bleeding.
Patients and methodology: In retrospective clinical survey we
evaluated 52 patients who died from complication of liver cirrhosis.
We considered death from variceal bleeding in those patients who
developed hemorrhage shock following severe hemathemesis and/or
melena. We confirmed bleeding from esophageal and fundus varices
by means of proximal endoscopy. All patients were hospitalized
in Division for Gastroenterohepatology, CCU Sarajevo, from January
1996. - December 1998. Results: Death from ruptured esophageal
varices was confirmed in 11/51 (21.5%) patients. Mortality rate
due to ruptured varices was higher in patients having cirrhosis
of virus (9/11; 81.8%) than of alcohol (2/11; 18.2%) (X2=6.545;
p< 0.011) etiology. Patients classified (prognostic classification
system of hepato-cellular function) as Child's Pugh B predominated
over Child Pugh A and C (p<0.01). Conclusion: Ruptured esophageal
varices (REV) are important cause of death in patients having
terminal and irreversible liver disease. Undertaking various therapeutic
procedures in patients having diagnosed esophageal varices certainly
ensure better survival.
Keywords: Ruptured esophageal varices, portal hypertension, mortality.