Aim of this study was investigation how stress caused by war influenced on morbidity and mortality of AMI and how did "post war release" contribute on incidence and mortality of acute coronary syndrome (ACS). 5 years periods were observed. Years 1991-1995 during the war and 5 post war years 1996-2000 were correlated to age and gender of patients. Total of 992 patients were observed (706 male, 286 female), with AMI in war and 583 (395 male and 188 female) in post war period. During the war we had 992 patients with AMI and in post war period number of patients were significantly lower, 583. Mortality of AMI in war period was 183 (18.44% of patients), 116 male, 67 female and in post war period mortality was 152 (26% of patients), 87 male and 65 female. Interestingly, number of deaths from AMI in post war period was still high. This could be explained with effect of "still present stress". This by all means implies that sympathetic tonus in war and in post war period was predominant risk factor for AMI and mortality of AMI

.Keywords: acute coronary syndrome, mortality, risk factors, stress