Unstable angina pectoris represents nowadays those clinical syndromes which according to their gravity fall somewhere between unstable angina pectoris and myocardial infraction with Q waves. After hospitalisation and anti-ischaemic and anti-thrombolytic treatment, the patients with unstable angina pectoris are discharged and sent homes with recommendation to take different medications. During the period of six months we studied 45 patients with unstable angina pectoris who had been before treated at the cardiological ward of the Internal Clinic in Tuzla. The patients were divided into 3 groups with the same number of patients (15 each). All 45 not hospitalised patients, were taking continuously one of the selective beta-blockers (atenolol, metoprolol) whosedoses ranged from 50-200mg and ASS 100mg (Aspirin Bayer, bospirin, Andol). Apart from that they were taking: - 1 group: Molsidomin 2x2mg - 2 group: Molsidomin 2mg in themorning and at noon and Olicard R. 40 or 60mg in evening During the period of six months there was no cardiac death only in Group 2, whilst there was one sudden cardiac death in Group i and two sudden cardiac deaths in Group 3. None of the patients from Group 2 were hospitalised again while the majority of patients from the other two groups (1 and 3) were hospitalised one or times more during the study period. Combined therapy with Olicard R or Molsidomin proved to bevery efficacious in preventing the recurrences of unstable angina pectoris.