Systematic artery hypertension is one of the most frequently found cardiac diseases in Bosnia and Herzegovina and it is the leading risk for the development of ischaemic cardiac disease.Artery hypertension treatment varies from patient to patient, and includes both non-pharmacological and pharmacological treatments. Material and methods: A prospective study of effects of «Nebivolol» was made on 80 non-hospitalized patients with minor and medium artery hypertension.The research lasted 8 weeks and included five visits to the doctor for each patient.Daily doses of Nebivolol ranged between 2,5 and 5 mg. During the examinations, the following parameters were observed: the value of artery pressure and heart frequency, the value of glycaemia, serum creatinine, cholesterol and triglycerides.ECG was made during the first and the fifth visit, and ultrasound of heart was made in 30 patients (the dimensions of septum and posterior wall of myocardium of left ventricle were measured).Side effects of the medicine were also observed. The results obtained show a considerable decrease in both systolic and diastolic artery pressures. It was also confirmed that the medicine was equally effective in men and women.No metabolic irregularities were found (increase of glycaemia, cholesterol or triglycerides). The only side effects which were noticed were headache and bradycardia.The treatment was not terminated because of these effects, only the doses were adapted.
Keywords: artery hypertension, beta-blockers (Nebivolol).