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Second Congress of Cardiology and Angiology of Bosnia & Herzegovina


.O. Terzić, M. Dilić, S. Pehar and A. Mlaćo
Institute of Vascular Diseases, Clinical Center University of Sarajevo, Sarajevo, Bosnia and Herzegovina

Background: Atherosclerosis is systemic disease with possible expression on various vascular beds, especially accelerated in diabetics. Aim of the study is to show possible connection between score of multiple risk factors (MRF) with localisation, clinical stage and outcome of arterial occlusive disease (AOD) in diabetics. Methods: Group of 61 diabetics (41 M, 20F) average age of 63.6 yrs. and average diabetes lasting 14.8 yrs, all of them in various stages of diabetic angiopathy was observed. According to their coronary heart disease (CHD) two groups were formed: group with clear clinical signs of CHD and group in which those signs are not proven (without any sign of CHD). Two groups were formed according to AOD: group with insufficiency of arterial flow without ischaemia (clinical stage Fontaine II)-20 pts. (32.8%), and group with clear ischaemic changes, diabetic ulceration or gangrene (clinical stage FIII/FIV)- 41 pts. (67.2%). According to coronary status two groups are formed: with clear clinical signs of CHD 34 pts (55.7%) and non-CHD group.. We observed 9 clinical variables: age, gender, hypertension (HTA), hyperlipoproteinemia (hlp), fibrinogen (fib), HbA1C, coronary heart disease (CHD), obesity (obes) and tobacco (tob). Patients were distributed as follows: age>60 yrs. 70.5%, male 67%, HTA 47.5%, hlp 29.5%, fib 46% (average 14.21 ?mol/l), HbA1C above normal 90.2% (average 8.33%), CHD 56%, obes. 20% and tob 52.5%. Score of MRF for entire group was 4.68 (x/9). Results: In a group of patients with unifocal expression (AOD) were 27 pts. (44.3%) with score of MRF of 4.2. In clinical stage FII 33% pts with score MRF 4.4 and in FIII/FIV 67% with MRF score of 4.1. In a group of patients with multifocal expression (AOD+CHD) were 34 pts (55.7%) and score of MRF 5.5. In clinical stage FII 32% with score of MRF 5.3, and in stage FIII/FIV 68% with score of MRF 5.6 Conclusion: According to clinical variables group was in high risk. Number of patients with multifocal atherosclerotic disease is significantly higher than those with unifocal what correlate with high score of MRF in both observed groups.

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