PREDICTORS OF LONG-TERM OUTCOME IN UNSTABLE ANGINA PECTORIS
Čolić, M. Mirić, A. Nešković and B. Đukanović
Cardiovascular Institute, Belgrade, Yugoslavia.
high-risk patients with unstable angina (UA) still represents
a clinical and therapeutical challenge. Aim: To determine independent
clinical and angiographic predictors of poor long-term outcome
in patients with UA. Method: A combined cardiac death and non-fetal
myocardial infarction (NFMI) as well as combined cardiac death,
NFMI an recurrent UA during follow-up (3913 months) was monitored
in 94 consecutive patients (61 males, aged 568.7 years) with confirmed
UA admitted to the CCU. The Cox univariate and multivariate survival
analyses were used to determine independent predictors. Results:
Cox univariate analysis revealed 6 predictors among many clinic
and angiographic variables: number of vessels diseased, diabetes,
previous MI, UA score, admission heart rate, 2mm or higher ST
depression in precordial leads. Predictors of combined death and
NFMI by Cox multivarlate analysis were: number of vessels diseased,
previous MI and 2mm or higher ST depression in precordial leads.
The only predictor of combined death, NFMI and recurrent UA by
multivariate analysis was number of vessels diseased. Conclusion:
The number of vessels diseased is the strongest predictor of poor
long-term outcome in our patients with UA.